| 丁酸在含氯化钙双水相体系中的有效分离(英文) |
| |
| 引用本文： | 吴丹,陈灏,江凌,蔡谨,徐志南,岑沛霖.丁酸在含氯化钙双水相体系中的有效分离(英文)[J].中国化学工程学报,2010,18(4):533-537. |
| |
| 作者姓名： | 吴丹 陈灏 江凌 蔡谨 徐志南 岑沛霖 |
| |
| 作者单位： | Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China |
| |
| 基金项目： | the National High Technology Research and Development Program of China，the National Basic Research Program of China，the Ministry of Science and Technology |
| |
| 摘 要： | One of the bottlenecks for bioproduction of butyric acid as bulk chemical is the difficulty in separating butyric acid from the fermentation broth,compared with the petroleum-based chemical synthesis method.In the present work,a novel separation methodology was developed based on an aqueous two-phase system with inor-ganic salts.Calcium chloride was screened out for effective separation of butyric acid from butyric acid-water-salt systems.Within appropriate concentration range of butyric acid and salt,butyric acid was enriched in the upper phase and most of calcium ions remained in the lower phase.This"salting out"effect is very efficient to separate butyric acid from the simulated butyrate fermentation broth,which consists of butyric acid and acetic acid with concentration ratio of 4︰1,so that the final ratio of butyric acid/acetic acid in the upper phase is improved to 9.87. The aqueous two-phase system was used to separate butyric acid from the actual fermentation broth with satisfac-tory result.
|
| 关 键 词： | butyric acid separation aqueous two-phase partition salting out effect calcium chloride |
| 收稿时间： | 2009-12-15 |
| 修稿时间： | 2009-12-15
|
Efficient separation of butyric acid by an aqueous two-phase system with calcium chloride |
| |
| WU Dan,CHEN Hao,JIANG Ling,CAI Jin,XU Zhinan,CEN Peilin.Efficient separation of butyric acid by an aqueous two-phase system with calcium chloride[J].Chinese Journal of Chemical Engineering,2010,18(4):533-537. |
| |
| Authors: | WU Dan CHEN Hao JIANG Ling CAI Jin XU Zhinan CEN Peilin |
| |
| Affiliation: | Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China;Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China;Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China;Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China;Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China;Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China |
| |
| Abstract: | One of the bottlenecks for bioproduction of butyric acid as bulk chemical is the difficulty in separating butyric acid from the fermentation broth,compared with the petroleum-based chemical synthesis method.In the present work,a novel separation methodology was developed based on an aqueous two-phase system with inor-ganic salts.Calcium chloride was screened out for effective separation of butyric acid from butyric acid-water-salt systems.Within appropriate concentration range of butyric acid and salt,butyr... |
| |
| Keywords: | butyric acid separation aqueous two-phase partition salting out effect calcium chloride |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《中国化学工程学报》浏览原始摘要信息 |
|
点击此处可从《中国化学工程学报》下载全文 |
|
