| Computer Simulation for Effect of Tb^3＋ on Ca^2＋ Speciation in Human Plasma |
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| 引用本文： | 卢兴,王悦,张海元,王进平,牛春吉,倪嘉缵. Computer Simulation for Effect of Tb^3＋ on Ca^2＋ Speciation in Human Plasma[J]. 中国稀土学报(英文版), 2002, 20(3): 238-240 |
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| 作者姓名： | 卢兴 王悦 张海元 王进平 牛春吉 倪嘉缵 |
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| 作者单位： | Key Laboratory of Rare Earth Chemistry and Physics，Changchun Institute of Applied Chemistry，Chinese Academy of Sciences，Changchun 130022，China |
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| 基金项目： | ProjectSupportedbytheNationalNaturalScienceFoundationofChina (2 9890 2 80,2 99710 2 9) |
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| 摘 要： | Ｂｅｃａｕｓｅｏｆｔｈｅｅｘｃｅｌｌｅｎｔｓｐｅｃｔｒｏｓｃｏｐｉｃａｎｄｍａｇｎｅｔｉｃｐｒｏｐｅｒｔｉｅｓｏｆｔｒｉ ｐｏｓｉｔｉｖｅｌａｎ ｔｈａｎｉｄｅｉｏｎｓｃｏｕｐｌｅｄｗｉｔｈｔｈｅｓｉｍｉｌａｒｉｔｉｅｓｂｅ ｔｗｅｅｎｔｈｅｍａｎｄＣａ2 + ｉｏｎｐａｒｔｉｃｕｌａｒｌｙｗｉｔｈｒｅ ｇａｒｄｔｏｉｏｎｉｃｒａｄｉｉ,ｌｉｇａｎｄｅｘｃｈａｎｇｅｒａｔｅｓａｎｄｃｏｏｒｄｉｎａｔｉｏｎｎｕｍｂｅｒｓ[1] ,ｍａｎｙｓｔｕｄｉｅｓｈａｖｅｆｏ ｃｕｓｅｄｏｎａｐｐｌｉｃａｔｉｏｎｏｆｌａｎ…
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| 关 键 词： | 稀土 计算机仿真 钙 铽 等离子体 |
Computer Simulation for Effect of Tb3+ on Ca2+Speciation in Human Plasma |
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| Abstract: | Effect of Tb 3+ on Ca 2+ speciation in human plasma was studied by means of the computer program of MINTEQA2. When Tb 3+ ions are not added into the system, Ca 2+ ions mostly distribute in free Ca 2+ (74.7%) and the surplus distributes in Ca 2+ complexes, such as [CaHCO 3] +(7.9%), [Ca(Lac)] +(6.4%), CaHPO 4 (1 3%), [CaHistidinateThreoninateH 3] 3+ (2.4%), [CaCitrateHistidinateH 2] (2.3%) and CaCO 3(1.1%). Tb 3+ can compete with Ca 2+ for inorganic as well as biological ligands. An increase of concentration of Tb 3+ in the system results in an increase of content of free Ca 2+ and a decrease of contents of Ca 2+ complexes. |
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| Keywords: | rare earths computer simulation speciation human plasma calcium terbium |
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