The Determination of Low-Level Water in Transdermal Dosage Forms as Tyvek Laminates with an Evaporator Oven |
| |
| Authors: | Stanton de Riel Imrana Mahmood Francisco Alvarez Shashank Mahashabde Sharad Govil |
| |
| Affiliation: |
a Schering-Plough Research Institute, Kenilworth, New Jersey |
| |
| Abstract: | An assay of water in adhesive monolithic transdermal drug dosage forms ('patches'), using lamination to Tyvek, and gaseous extraction in an evaporator oven into a Karl Fischer titrator, is described. The method is simple, linear, accurate, specific and more sensitive than alternatives. |
| |
| Keywords: | |
| 本文献已被 InformaWorld 等数据库收录！ |
|
