| Abstract: | Formation of Ethoxyhydroquinazolinone by Attack of an Estercarbonyloxygen at a Cyano Group By the reaction of ethyl-2-oxo-cyclohexanecarboxylate with cyan amide 4-ethoxyhexahydroquinazolin-2-one (12) is formed. Butyl-2-oxo-cyclopentanecarboxylate and cyan amide yield butyl-3-cyanamino-cyclopent-1-en-carboxylate (14) . 2-Oxocyclohexane-carboxamide (1) and ethyl-cyanoacetate form with sodiumhydroxide 4-cyano-octahydroisoquinolin-1, 3-dione (17) and with ammonium acetate ethyl cyclohexylidene-cyanoacetate-2-carboxamide (18) . 18 and ammonia, hydrazine, or cyclohexylamine form the salts of cyanohydroquinazolindione 20a–c , respectively. |
