| 桔霉素与红曲霉的安全性争议 |
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| 引用本文： | 张徐兰,吴天祥,李鹏.桔霉素与红曲霉的安全性争议[J].酿酒科技,2007(1):81-83. |
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| 作者姓名： | 张徐兰 吴天祥 李鹏 |
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| 作者单位： | 1. 贵州大学化学工程学院,贵州,贵阳,550003
2. 莱阳农学院食品学院,山东,青岛,266003 |
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| 摘 要： | 红曲霉能代谢生成天然红色素和多种生理活性物质而备受国际关注,但同时也发现其生长过程产生桔霉素.桔霉素是一种真菌毒素,作用的靶器官是肾脏,可以致畸、诱发肿瘤、突变等.红曲霉中桔霉素的发现使得我国的红曲产品的安全性引起争议.介绍了红曲中产生的桔霉素的理化性质、毒性、产生途径和检测方法等的研究现状,并就如何消除红曲中桔霉素提出了对策.
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| 关 键 词： | 桔霉素 红曲霉 安全 争议 桔霉素 红曲霉 安全性 对策 现状 研究 检测方法 产生途径 毒性 理化性质 红曲产品 突变 诱发肿瘤 肾脏 靶器官 作用 真菌毒素 过程产生 生长 发现 |
| 文章编号： | 1001-9286(2007)01-0081-03 |
| 修稿时间： | 2006-10-23 |
Dispute about the Safety of Citrinin of Monascus |
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| ZHANG Xu-lan,WU Tian-xiang,LI Peng.Dispute about the Safety of Citrinin of Monascus[J].Liquor-making Science & Technology,2007(1):81-83. |
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| Authors: | ZHANG Xu-lan WU Tian-xiang LI Peng |
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| Affiliation: | 1.Chemical Engineering Department of Guizhou University, Guiyang, Guizhou 550003; 2.Food Science Engineering Department of Laiyang Agriculture College., Qingdao ,Shandong 266003, China |
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| Abstract: | Monascus, as a physiologically active substance and an old-line fermentable epiphyte in China, has been studied widely for its natural pigments. However, citrinin, produced in the growth process ofmonascus, is a myeotoxin and will induce teratogenicity, carcinogenicity and mutagencity. Accordingly, the discovery of eitrinin in monascus brought tremendous dispute about the safety of red starter products. In this paper, the physical and chemical properties, the toxicological characteristics, the biosynthetic pathway and the detection method of citrinin produced in monascus were introduced and the relative counter measures to eliminate citrinin were also illustrated. |
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| Keywords: | citrinin Monascus safety dispute |
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