13C-UBT诊断Hp的临床价值

通过对100例胃肠道功能紊乱的患者进行胃镜检查、活组织检查、胃窦活检快速Hp检查、^13C-尿素呼气试验(^13C-UBT)和ASSURE^TM Hp快速试验(HpRT)，并以胃镜活检和组织病理检查结果为金标准。结果显示：胃窦活检快速Hp检查法的灵敏度为79％，特异性为76％；^13C—UBT检查的灵敏度为96％，特异性为95％；HpRT检查的灵敏度为86％，特异性为88％。^13C-UBT检查Hp的灵敏度和特异性较好，可作为临床上诊断Hp的首选方法。

Clinical Value of 13C-UBT Diagnosing Infection of the Hp

100 dyspeptic patients are performed an endoscopy with biopsy for histology, rapid urease test,13C-urea breath test(13C-UBT) and ASSURE?Hp rapid Test(HpRT). Patients are considered to be infected if both histology and biopsies yield positive results, and not infected when both tests are negative. The pathology and persons responsible for endoscopy, urease test and 13C-UBT are unaware of the results from the other diagnostic methods. The 13C-UBT has the following results: sensitivity 96% .specificity 95% ; rapid urease test has the following results: sensitivity 79% , specificity 76%; HpRT has the following results; sensitivity 86% .specificity 88%. 13C-UBT provides excellent sensitivity and specificity for the diagnosis of Hp. Pylori infected Hp, it can be the first choice for detecting the infection of the Hp.