Tracking the gatekeeper gene in the stages of carcinogenesis in the bladder |
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Authors: | E Baud P Catilina YJ Bignon |
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Affiliation: | Dipartimento di Chimica, Politecnico di Milano, Italy. |
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Abstract: | From Dragon's Blood, a resin produced by plants of the genus Daemonorops (Palmae), six new A-type flavanoid deoxyproanthocyanidins have been isolated. Their structure and stereochemistry, established by chemical degradation and extensive NMR analysis, is consistent with a mechanism of formation common to other constituents of the resin, which involves oxidation of a 6-methylflavan to a quinonemethide, followed by coupling with another flavan moiety. |
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