| 太子参醇提物的抗脂质过氧化作用 |
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| 引用本文： | 袁逸铭,高湘,许爱霞,葛斌.太子参醇提物的抗脂质过氧化作用[J].金属学报,2005,10(1):83-86. |
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| 作者姓名： | 袁逸铭 高湘 许爱霞 葛斌 |
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| 作者单位： | 兰州医学院第二附属医院耳鼻喉科, 兰州 730030, 甘肃;1.甘肃省人民医院药剂科, 兰州 730030, 甘肃 |
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| 基金项目： | 甘肃省科学事业科研项目(NoQS041-C33-20) |
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| 摘 要： | 目的: 研究太子参醇提物的抗脂质过氧化作用。方法: 用自然衰老模型大鼠, 同时灌胃给予生药量2.16、4.32、8.64 g·kg-1·d-1的醇提物, 观察其对自然衰老模型大鼠抗氧化系统的影响。结果: 生药量2.16、4.32、8.64 g·kg-1·d-1的太子参醇提物能使自然衰老模型大鼠血清、肝、肾组织中MDA 不同程度下降, 而SOD 及GSH-PX 活力有不同程度提高。结论: 太子参醇提物有显著清除氧自由基、活性氧及抗脂质过氧化作用。
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| 关 键 词： | 太子参醇提物 氧自由基 活性氧 脂质过氧化 丙二醛 超氧化物歧化酶 谷胱甘肽过氧化物酶 大鼠 |
| 收稿时间： | 2004-10-14 |
| 修稿时间： | 2004-11-16 |
Effects of alcoholic extract from Radix Pseudostellariae (ERP)on antilipoperoxidation |
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| YUAN Yi-ming,GAO Xiang,XU Ai-xia,GE Bin.Effects of alcoholic extract from Radix Pseudostellariae (ERP)on antilipoperoxidation[J].Acta Metallurgica Sinica,2005,10(1):83-86. |
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| Authors: | YUAN Yi-ming GAO Xiang XU Ai-xia GE Bin |
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| Affiliation: | Department of Otorhinolaryngology, the Second Affiliated Hospital, LanzhouMedical College, Lanzhou 730030, Gansu, China;1.Department of Pharmaceutics, People's Hospital of Gansu Province, Lanzhou 730030, Gansu, China |
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| Abstract: | AIM: To study the effects of the alcoholic extract from Radix Pseudostellariae(ERP)on antilipoperoxidation.METHODS: The effects of ERP on antioxidation systems of rats were observed by natural senile model rats which were administered the alcoholic extract from 2.16, 4.32, and 8.64 g·kg-1·d-1 of Radix Pseudostellariae.RESULTS: MDA decreased and the activities of SOD and GSH-PX increased in serum, liver and kidneys of natural senile model rats administered ERP.CONCLUSION: ERP have the notable effect on eliminating oxygen free radicals, active oxygen and antilipoperoxidation. |
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| Keywords: | Radix Pseudostellariae oxygen free radicals active oxygen antilipoperoxidation malondialdehyde superoxide dismutase glutathione peroxidase rats |
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