LC50 estimates and their confidence intervals derived for tests with only one concentration with partial effect |
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Authors: | Nelly van der Hoeven |
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Abstract: | Linear approximation fails to determine the likelihood based confidence interval for the LC50 parameter in a toxicity experiment with only one concentration causing partial mortality. An equation for this confidence interval is derived given a log-logistic concentration response relation. A table of the 95 and 99% confidence intervals is given for the case that partial survival occurs only at one concentration, under the condition that a fixed number of animals is used at each test concentration and a constant ratio is used between the test concentrations. |
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Keywords: | LC50 estimates confidence intervals ecotoxicity |
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