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Changes in the chemical composition of surfactant-like particles secreted by rat small intestine in response to different dietary fats
Authors:Kalra Seema  Mahmood Safrun  Nagpaul J P  Mahmood Akhtar
Affiliation:(1) Department of Biochemistry, Panjab University, Sector 14, 160014 Chandigarh, India;(2) Department of Experimental Medicine, Post Graduate Institute of Medical Education and Research, Sector 14, 160012 Chandigarh, India
Abstract:Consumption of dietary oil, viz., corn, fish, coconut, or olive, induced the secretion of surfactant-like particles (SLP) in rat intestine. These lipoprotein particles differ in (i) levels of alkaline phosphatase activity, (ii) lipid composition, and (iii) FA composition in response to feeding of different oils. The secreted particles had similar buoyancy (1.07–1.08 g/mL) and cholesterol/phospholipid molar ratios (0.61–0.72) except that feeding coconut oil to rats produced SLP with a low (0.18) cholesterol/phospholipid molar ratio compared to control animals. It is concluded from these observations that feeding different oils induces the secretion of lipoprotein particles in rat intestine with different chemical compositions.
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