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Distinct Gene Set Enrichment Profiles in Eosinophilic and Non-Eosinophilic Chronic Rhinosinusitis with Nasal Polyps by Bulk RNA Barcoding and Sequencing |
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| Authors: | Takashi Ishino Sachio Takeno Kota Takemoto Kensuke Yamato Takashi Oda Manabu Nishida Yuichiro Horibe Nobuyuki Chikuie Takashi Kono Takayuki Taruya Takao Hamamoto Tsutomu Ueda |
| Affiliation: | Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Kasumi 1-2-3, Hiroshima 734-8551, Japan; (T.I.); (K.T.); (K.Y.); (T.O.); (M.N.); (Y.H.); (N.C.); (T.K.); (T.T.); (T.H.); (T.U.) |
| Abstract: | |
| Keywords: | paranasal sinuses chronic rhinosinusitis (CRS) BRB-seq CRS endotypes nasal polyps eosinophils differentially expressed genes (DEGs) analysis database for annotation visualization and integrated discovery (DAVID) pathway analysis type 2 inflammation |