Impedance analysis of a phosphatidylcholine-phosphatidylethanolamine system in bilayer lipid membranes |
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| Authors: | Monika Naumowicz Aneta Dorota Petelska |
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| Affiliation: | a Institute of Chemistry, University of Bialystok, Al. J. Pilsudskiego 11/4, 15-443 Bialystok, Poland
b Laboratory of Electrochemical Power Sources, Faculty of Chemistry, University of Warsaw, Pasteur St. 1, 02-093 Warsaw, Poland |
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| Abstract: | Electrochemical impedance spectroscopy was used for the study of two-component lipid membranes. Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) were to be investigated, because of their presence in biological membranes. Capacitance values of pure components are 0.62 and 0.32 μF cm−2, respectively. The 1:1 complex was formed during formation of the PC-PE lipid membrane. Formation of the complex can explain the deviation from the additivity rule. This equilibrium was described by mathematical equations and was further verified experimentally. Adequate equations let us calculate such parameters as: capacitance of the complex molecule, area occupied by the complex molecule as well as the stability constant of the complex. |
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| Keywords: | Impedance spectroscopy Phosphatidylcholine Phosphatidylethanolamine Complex 1:1 |
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