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葵花籽ACE抑制肽的体内降压活性初步研究
引用本文:罗鹏,周金玲,何东平,潘思轶. 葵花籽ACE抑制肽的体内降压活性初步研究[J]. 粮食与油脂, 2019, 32(2): 19-22
作者姓名:罗鹏  周金玲  何东平  潘思轶
作者单位:石河子大学食品学院,新疆石河子,832003;新疆石河子开发区神内食品有限公司,新疆石河子,832000;武汉轻工大学食品科学与工程学院,湖北武汉,430023;华中农业大学食品科技学院,湖北武汉,430070
摘    要:以自发性高血压大鼠(SHR)建立试验模型,探讨葵花籽ACE抑制肽的体内降压活性。试验结果表明:一次性给药后,葵花籽ACE抑制肽各剂量组对SHR收缩压的降低作用存在明显的量效关系,且降压活性具有时效性;长期灌胃葵花籽ACE抑制肽,SHR体重均呈增加趋势,其中剂量组大鼠体重的增加量居于对照组和阳性对照组之间;在为期4周的长期给药试验中,除低剂量组外,其余各组均与对照组相比有显著的差异;各试验组SHR的心率值之间无显著差异性,表明葵花籽ACE抑制肽对SHR心率无显著的副作用。

关 键 词:葵花籽  ACE抑制肽  自发性高血压大鼠  体内降压活性

Preliminary study on antihypertensive activity of ACE inhibitory peptides from sunflower seeds in vivo
LUO Peng,ZHOU Jin-ling,HE Dong-ping,PAN Si-yi. Preliminary study on antihypertensive activity of ACE inhibitory peptides from sunflower seeds in vivo[J]. Cereals & Oils, 2019, 32(2): 19-22
Authors:LUO Peng  ZHOU Jin-ling  HE Dong-ping  PAN Si-yi
Affiliation:(Food College of Shihezi University,Shihezi 832003,Xinjiang,China;Shihezi Economic Development Zone Jinnai Food Co.,Ltd,Shihezi832000,Xinjiang,China;College of Food Science and Engineering of Wuhan Polytechnic University,Wuhan430023,Hubei,China;College of Food Science and Technology of Huazhong Agriculture University,Wuhan430070,Hubei,China)
Abstract:LUO Peng;ZHOU Jin-ling;HE Dong-ping;PAN Si-yi(Food College of Shihezi University,Shihezi 832003,Xinjiang,China;Shihezi Economic Development Zone Jinnai Food Co.,Ltd,Shihezi832000,Xinjiang,China;College of Food Science and Engineering of Wuhan Polytechnic University,Wuhan430023,Hubei,China;College of Food Science and Technology of Huazhong Agriculture University,Wuhan430070,Hubei,China)
Keywords:sunflower seed  ACE inhibitory peptides  spontaneous hypertensive rat  hypobaric activity in vivo
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