Anti-bacterial biofilm activity of magnesium ferrite thin film

ABSTRACT

Thin films of magnesium ferrite (MgFe₂O₄) are synthesized on the glass substrate by using thermal evaporation technique and studied their anti-bacterial biofilm activity against the gram-negative and gram-positive bacterium. The MgFe₂O₄ thin films (100 nm) were prepared at a deposition rate of 10 ± 2 Å/S, followed by annealing at 600°C. The morphological and structural study using scanning electron microscope, X-ray diffraction, and transmission electron microscope reveals crystalline structure of the magnesium ferrite. The model organisms for anti-bacterial biofilm activity were tested with E. coli (gram negative) and S. aureus (gram positive). The E. coli and S. aureus biofilms grown on the glass slides and MgFe₂O₄ coated glass slide were imaged using fluorescent microscope. It is observed that the MgFe₂O₄ coated glass slides exhibit minimum bacterial growth (both negative and positive bacteria) compared to the uncoated glass slide.