| A New General Linear Convolution Model for fMRI Data Process |
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| 引用本文： | YUANHong CHENHua-fu YAODe-zhong. A New General Linear Convolution Model for fMRI Data Process[J]. 中国电子科技, 2005, 3(1): 68-71 |
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| 作者姓名： | YUANHong CHENHua-fu YAODe-zhong |
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| 作者单位： | [1]SchoolofLifeScienceandTechnology,UESTCChengdu610054China [2]SchoolofLifeScienceandTechnology,UESTCChengdu610054China／／SchoolofAppliedMathematics,UESTCChengdu610054China |
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| 基金项目： | Supported by National Natural Science Foundation of China (No.90208003, 30200059), the 973 Project (No. 2003CB716106), Doctor training Fund of MOE, P.R.C., and Fok Ying Tong Education Foundation (No.91041) |
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| 摘 要： | General linear model (GLM) is the most popular method for functional magnetic resource imaging (fMRI) data analysis. However, its theory is imperfect. The key of this model is how to constitute the design-matrix to model the interesting effects better and separate noises better. For the purpose of detecting brain function activation, according to the principle of GLM, a new convolution model is presented by a new dynamic function convolving with design-matrix, which combining with t-test can be used to detect brain active signal. The fMRI imaging result of visual stimulus experiment indicates that brain activities mainly concentrate among vland v2 areas of visual cortex, and also verified the validity of this technique.
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| 关 键 词： | fMRI 数据处理 血液动力反应 褶积模型 GLM |
A New General Linear Convolution Model for fMRI Data Process |
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| YUAN Hong,CHEN Hua-fu,Yao De-zhong. A New General Linear Convolution Model for fMRI Data Process[J]. Journal of Electronic Science Technology of China, 2005, 3(1): 68-71 |
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| Authors: | YUAN Hong CHEN Hua-fu Yao De-zhong |
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| Affiliation: | 1. School of Life Science and Technology, UESTC Chengdu 610054 China
2. School of Life Science and Technology, UESTC Chengdu 610054 China;School of Applied Mathematics, UESTC Chengdu 610054 China |
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| Abstract: | General linear model (GLM) is the most popular method for functional magnetic resource imaging (fMRI) data analysis . However, its theory is imperfect. The key of this model is how to constitute the design-matrix to model the interesting effects better and separate noises better. For the purpose of detecting brain function activation , according to the principle of GLM,a new convolution model is presented by a new dynamic function convolving with design-matrix,which combining with t-test can be used to detect brain active signal. The fMRI imaging result of visual stimulus experiment indicates that brain activities mainly concentrate among v1and v2 areas of visual cortex, and also verified the validity of this technique. |
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| Keywords: | fMRI general linear model t-test hemodynamic response function |
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