The four-electrode resistivity technique in anisotropic media:theoretical analysis and application on myocardial tissue in vivo |
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Authors: | Steendijk P Mur G Van Der Velde ET Baan J |
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Affiliation: | Dept. of Cardiology, Leiden Univ. Hospital; |
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Abstract: | Several aspects of the 4-electrode resistivity technique were studied with special emphasis on the theoretical determination of penetration depth and sample volume in anisotropic media such as (cardiac) muscle. Moreover, the presence of a thin disturbing layer on top of the medium under study was analyzed. A 4-electrode sensor was developed for the measurement of local myocardial resistivity in 2 orthogonal directions. The sensor was applied to the epicardium of anesthetized open chest dogs and, as an example, results are given on the frequency dependence (5-60 kHz) and the changes during the cardiac cycle of longitudinal and transverse myocardial resistivity |
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