分子筛辅助人参须根粉快速制备人参皂苷Rg5的工艺研究

利用多功能改进型索氏提取器为提取工具，以人参须根粉为原料，盐酸为催化剂，分子筛辅助下高效制备了稀有人参皂苷Rg5，并通过单因素实验优化了工艺条件。实验结果表明：当以30 mL的甲醇为溶剂、加入0.3 g 4 A分子筛、于65 ℃提取4 h时，人参总皂苷的提取率达到10.2%，稀有人参皂苷Rg5的得率达到3.20%，与传统索氏提取器相比可以显著提高人参皂苷Rg5的制备效率。分子筛辅助下利用多功能改进型索氏提取器从人参须根粉提取制备稀有人参皂苷Rg5，不仅得率较高，而且操作简单快捷，是一种快速制备人参皂苷Rg5的工艺方法。

An Efficient Synthesis of Ginsenoside Rg5 Via Conversion from Ginseng Fibrous Root Powder in the Presence of Molecular Sieves

The rare ginsenoside Rg5 was efficiently prepared in the presence of molecular sieves. using the multi-functional improved Soxhlet extractor as extraction tool and ginseng fibrous root powder as raw material, hydrochloric acid as catalyst. The extraction process of ginsenoside Rg5 was optimized through one-factor experiment. The optimum result obtained from one-factor test was as follows: extraction solvent was 30 mL methanol, 4A molecular sieve was 0.3 g, the heating temperature in the extraction barrel was 65 ℃, and extraction time was 4 h. Under the optimized conditions, the extraction yield of total ginsenosides reached 10.2% and the yield of rare ginsenoside Rg5 was 3.20%, which could significantly improve the preparation efficiency of ginsenoside Rg5 compared with the traditional Soxhlet extractor. The method has following characteristics such as high extraction yield and simple operation, which indicated the method could extract Rg5 effectively.