类风湿性关节炎缓解后的维持治疗研究进展

类风湿性关节炎(RA)是一种以关节的炎症损害为主要特点的复杂、多系统自身免疫性疾病。关于RA缓解期的药物使用一直是长期以来困扰风湿病学界的难点和热点。近年随着改变病情抗风湿药的日益成熟、生物制剂的快速发展,使RA的维持治疗手段和药物选择更具灵活性, 疗效、预后和药物不良事件控制较以往均有新的突破。本文就缓解后治疗的最新研究作一综述。

Development of maintenance treatment about rheumatoid arthritis in remission

Rheumatoid arthritis (RA) is a kind of complex and multi-system autoimmune disease with the main characteristics of the inflammation in joints .About the drug use of RA in remission is always a difficult and hot problem in rheumatology academia for a long time. In recent years, with the maturity of DMARDs and the rapid development of biological agents, the maintenance treatment and drug selection in RA is more flexible. New breakthrougs about curative effect, prognosis and the control of adverse events have been made in the past few years. Now the maintenance treatment of rheumatoid arthritis in remission was reviewed.