| 树脂层析法脱色和浓缩紫杉醇 |
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| 引用本文： | 张志强 许建峰. 树脂层析法脱色和浓缩紫杉醇[J]. 高校化学工程学报, 1999, 13(2): 161-164 |
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| 作者姓名： | 张志强 许建峰 |
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| 作者单位： | 大连理工大学生化工程研究所!大连１１６０１２ |
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| 摘 要： | １前言紫杉醇（Ｐａｃｌｉｔａｘｅｌ，商品名Ｔａｘｏｌ）是红豆杉属植物中独有的一种抗肿瘤天然药物，由美国化学家Ｗａｎｉ和Ｗａｌｌ［１］等人于１９７１年首次分离得到，并于１９９２年被美国ＦＤＡ正式批准为抗卵巢癌新药。由于其独特的抗癌作用机制及显著的疗效而...
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| 关 键 词： | 紫杉醇 大孔网状 吸附树脂 层析 脱色 浓缩 |
Decoloration and Separation of Paclitaxel from Taxus Yunnanensis Extract by Macroreticular Adsorbent Resin |
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| Zhang Zhiqiang, Xu Jianfeng, Su Zhiguo. Decoloration and Separation of Paclitaxel from Taxus Yunnanensis Extract by Macroreticular Adsorbent Resin[J]. Journal of Chemical Engineering of Chinese Universities, 1999, 13(2): 161-164 |
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| Authors: | Zhang Zhiqiang Xu Jianfeng Su Zhiguo |
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| Abstract: | The macroreticular adsorbent resin was used for separation of paclitaxel from TaxusYunnanensis extract. The suitable operation conditions for adsorption and elution were explored. Withpolystyrene resin as adsorbent and 80% CH3OH(pH6.4) as eluent, both decoloration and purificationcan be achieved. The Paclitaxel recovery was 99.6%. |
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| Keywords: | Paclitaxel Macroreticular adsorbent resin Chromatography |
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