二甲基甘氨酸钠对肉鸡生长发育及抗氧化能力的影响

研究食品抗氧化剂二甲基甘氨酸钠（N,N-dimethylglycine sodium salt，Na-DMG）对肉鸡器官指数、血液生理生化指标及抗氧化功能的影响。选用1 日龄爱拔益加（Arbor Acres，AA）肉鸡720 只，随机分成6 组，每组6 个重复，对照组饲喂基础日粮，实验组在基础日粮中添加300、500、1 000、1 500、2 000 mg/kg二甲基甘氨酸钠。结果表明：日粮中添加2 000 mg/kg的二甲基甘氨酸钠可显著提高肉鸡的脾脏指数（P＜0.05）；与对照组相比，添加剂量为1 000 mg/kg的二甲基甘氨酸钠组肉鸡生长前期血液中三碘甲状腺原氨酸（triiodothyronine，T3）的含量显著提高（P＜0.05），二甲基甘氨酸钠对肉鸡生长后期血液中的生理生化指标无显著影响（P＞0.05）；二甲基甘氨酸钠对肉鸡血清和肝脏的总抗氧化能力影响较为显著。肉鸡生长后期，添加剂量在500 mg/kg以上的二甲基甘氨酸钠组肉鸡的血清中T-AOC活力显著提高（P＜0.05）；1 000 mg/kg以上的二甲基甘氨酸钠则能显著提高肉鸡肝脏的T-AOC活力（P＜0.05）。二甲基甘氨酸钠可有效促进肉鸡胰腺的发育，增强肉鸡的免疫功能，并能显著提高肉鸡的抗氧化能力，且以1 000～2 000 mg/kg的添加剂量效果最佳。

Effect of N,N-dimethylglycine Sodium Salt on Organ Indexes,Blood Physiobiochemical Indices and Antioxidative Performance of Broilers

The present study was conducted to evaluate the effects of N,N-dimethylglycine sodium salt (Na-DMG) on organ
indexes, blood physiobiochemical indices and anti-oxidative performance of broilers. A total of 720 one-day-old AA broilers
were randomly allocated into six groups with 6 broilers in each group, and fed with a commercial starter diet supplemented
with Na-DMG at 0, 300, 500, 1 000, 1 500 and 2 000 mg/kg, respectively, for 42 days. The results showed that 1) dietary
supplementation of Na-DMG at 2 000 mg/kg improved significantly the spleen index of broilers (P < 0.05); 2) compared
with the control group, Na-DMG supplementation at 1 000 mg/kg increased significantly the blood triiodothyronine
(T3) level of 21-day-old broilers (P < 0.05), but had no significant effect on blood physiobiochemical indices of
42-day-old broilers (P > 0.05); 3) dietary Na-DMG mainly affected the total antioxidant capacity (T-AOC) in blood
and liver and at concentrations above 500 mg/kg improved significantly the blood T-AOC level of 42-day-old broilers
(P < 0.05), as well as at concentrations above 1 000 mg/kg increased the liver T-AOC level compared with the control
group (P < 0.05). In conclusion, dietary Na-DMG can promote the development of the pancreas effectively, enhance
the immune function and significantly increase the antioxidant capacity of broilers, especially when supplemented at
concentrations at 1 000–2 000 mg/kg.