Solvent‐free synthesis of chiral molecularly imprinted polymers: Porosity control using a nano‐sized solid porogen |
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| Authors: | Mariana Duarte Johan Billing Ecevit Yilmaz |
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| Affiliation: | 1. MIP Technologies AB, A Subsidiary of Biotage AB, Lund, Sweden;2. Department of Biomedical Engineering, Division of Nanobiotechnology, Lund University, Lund, Sweden |
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| Abstract: | Molecularly imprinted polymers (MIPs) have been synthesized in the absence of a solvent using fumed silica nanoparticles to create a porous network. The method employed led to a chiral imprinting effect and allowed for an excellent control over the internal morphology of imprinted and non‐imprinted polymer (NIP) materials. The polymers possess high surface areas (>300 m2) and identical pore size (112 Å). The MIP exhibited an imprinting factor (IF) of 9 and a selectivity value (α) of 1.83 for (?)‐ephedrine. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133, 44104. |
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| Keywords: | molecular recognition morphology nanoparticles porous materials |
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