Effect of pre‐germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats |
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Authors: | Shahin Roohinejad Alireza Omidizadeh Hamed Mirhosseini Nazamid Saari Shuhaimi Mustafa Rokiah Mohd Yusof Anis Shobirin Meor Hussin Azizah Hamid Mohd Yazid Abd Manap |
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Affiliation: | 1. Department of Food Technology, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia;2. Department of Nutrition, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia;3. Department of Food Science, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia;4. Halal Products Research Institute, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia |
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Abstract: | BACKGROUND: Brown rice is unpolished rice with immeasurable benefits for human health. Brown rice (BR) and pre‐germinated brown rice (PGBR) are known to contain various functional compounds such as γ‐oryzanol, dietary fibre and γ‐aminobutyric acid (GABA). In the present study, the experimental diets containing BR and PGBR (24, 48 h pre‐germination) were used to investigate the influence of pre‐germination time of brown rice on blood cholesterol in Sprague–Dawley male rats. RESULTS: Hypercholesterolaemia and elevation of LDL‐cholesterol were successfully ameliorated by the experimental diets containing BR and PGBR (24 and 48 h pre‐germination). As compared to the control sample, the pre‐germination time had a significant (P < 0.05) effect on blood cholesterol of Sprague–Dawley male rats. It was also found that the significantly (P < 0.05) better effect on lipid profile of hypercholesterolaemic rats was observed by prolonging the pre‐germination time. As compared to non‐germinated brown rice, the germinated brown rice showed the higher cardio‐protective effect on hypercholesterolaemic Sprague–Dawley male rats. CONCLUSION: The present study suggests that the changes of blood cholesterol can be mainly modulated by using the PGBR rather than BR. The prolonging of pre‐germination time led to an increase in the bioactive components, thereby providing a more efficient functional diet affecting the high blood cholesterol. This study suggests that PGBR can be used instead of BR and polished rice in the human diet. Copyright © 2009 Society of Chemical Industry |
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Keywords: | brown rice pre‐germination γ ‐oryzanol dietary fibre γ ‐amino butyric acid (GABA) hypercholesterolaemia |
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