| 高效液相色谱法在抗氧剂1520质量控制中的应用 |
| |
| 引用本文： | 高静,者东梅,郭燕玲,唐跃兵,范彦如.高效液相色谱法在抗氧剂1520质量控制中的应用[J].化学工业与工程技术,2012,33(3):18-20. |
| |
| 作者姓名： | 高静 者东梅 郭燕玲 唐跃兵 范彦如 |
| |
| 作者单位： | 中国石油化工股份有限公司北京化工研究院,北京,100013 |
| |
| 摘 要： | 研究了用HPLC分析抗氧剂1520(2,4-二(正辛硫基亚甲基)-6-甲基苯酚)含量的方法。采用Waters 2695-2996型高效液相色谱仪、Waters SunFireTMC18色谱柱,以甲醇和水混合溶剂(体积比95∶5)做流动相,流速1.0mL/min,紫外检测波长285nm的条件时,样品中的各组分达到较好的分离效果。2,4-二(正辛硫基亚甲基)-6-甲基苯酚质量浓度在0.2～2.0mg/mL范围内与色谱峰面积(A)呈线性关系,线性回归方程为A=140.17c-28.74,相关系数R2=0.995 4。采用外标法单点校正峰面积定量,对抗氧剂1520标准溶液测定的回收率为99.96%～100.24%。
|
| 关 键 词： | 2 4-二(正辛硫基亚甲基)-6-甲基苯酚 高效液相色谱 抗氧剂 |
Application of HPLC in quality control of 2, 4-bis(n-octylthiomethyl)-6-methylphenol in antioxidant 1520 |
| |
| GAO Jing
,
ZHE Dongmei
,
GUO Yanling
,
TANG Yuebing
,
FAN Yanru.Application of HPLC in quality control of 2, 4-bis(n-octylthiomethyl)-6-methylphenol in antioxidant 1520[J].Journal of Chemical Industry & Engineering,2012,33(3):18-20. |
| |
| Authors: | GAO Jing ZHE Dongmei GUO Yanling TANG Yuebing FAN Yanru |
| |
| Affiliation: | (SINOPEC Beijing Research Institute of Chemical Industry, Beijing 100013, China) |
| |
| Abstract: | The method for determining the content of 2, 4-bis（n-octylthiomethyl）-6-methylphenol in antioxidant 1520 by HPLC is studied. The determination is performed on the Waters 2695-2996 HPLC with Waters SunFireTMC18 column. The mobile phase consists of methanol and distilled water （95 ： 5, volume ratio） with the flow rate of 1.0 mL/min. UV detection is employed with the wavelength at 285 nm. Under the optimized conditions, the compounds from the sample are completely separated. The concentration of 2, 4-bis（n-octylthiomethyl）-6-methylphenol appears linear relation with peak area in the range of 0.2 to 2.0 mg/mL. The linear equation is A=140. 17c-28.74（Rz =0. 995 4）. The recovery of the analysis is in the range of 99. 96% to 100.24%. |
| |
| Keywords: | 2 4-Bis（n-octylthiomethyl）-6-methylphenol HPLC Antioxidant |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
