Polymerase chain reaction amplification of Trichomonas vaginalis DNA from Papanicolaou-stained smears |
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Authors: | T Okuyama R Takahashi M Mori M Osaka TK Kobayashi S Maeda |
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Affiliation: | Department of Pathology and Cytology, Karolinska Hospital, Stockholm, Sweden. |
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Abstract: | We describe 3 cases of Hodgkin's disease (HD) of unusual suppurative type, which were diagnosed on fine-needle aspirates. The smears were dominated by neutrophils, macrophages, and cellular debris. Only a few large, atypical cells of Hodgkin and Reed-Sternberg type were observed. The differential diagnoses of such smears include infectious mononucleosis, tuberculosis, metastatic lymph node involvement, non-Hodgkin's large-cell anaplastic Ki-1-positive lymphomas, T-cell-rich B-cell lymphomas, and peripheral T-cell lymphomas of mixed type. Immunocytochemistry identified the large atypical cells as CD 30 (BerH2)-positive and negative for CD 45 (LCA) in cytospin material from 2 patients, which allowed a conclusive diagnosis of HD. |
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