A new gene family (ariel) encodes asparagine-rich Entamoeba histolytica antigens, which resemble the amebic vaccine candidate serine-rich E. histolytica protein |
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| Authors: | Z Mai J Samuelson |
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| Affiliation: | Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts 02125, USA. |
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| Abstract: | A family of genes, called ariel, are named for and encode asparagine-rich Entamoeba histolytica antigens containing 2 to 16 octapeptide repeats. Ariel proteins, which are constitutively expressed by trophozoites, belong to a large antigen family that includes the serine-rich E. histolytica protein (SREHP), an amebic vaccine candidate. |
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