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Bacterial adherence on UHMWPE with vitamin E: an in vitro study
Authors:E. Gómez-Barrena  J. Esteban  D. Molina-Manso  H. Adames  M. J. Martínez-Morlanes  A. Terriza  F. Yubero  J. A. Puértolas
Affiliation:1.Department of Orthopaedic Surgery,Hospital La Paz,Madrid,Spain;2.Autónoma University of Madrid,Madrid,Spain;3.IIS-FJD, Department of Microbiology,Madrid,Spain;4.Department of Material Science and Technology, EINA-I3A,Zaragoza University,Zaragoza,Spain;5.Instituto Ciencia de Materiales de Sevilla, ICMSE,Seville University-CSIC,Seville,Spain;6.Instituto Ciencia de Materiales de Aragón, ICMA,Zaragoza University-CSIC,Zaragoza,Spain;7.Serv Cirugía Ortopédica y Traumatología A, Facultad de Medicina,Madrid,Spain
Abstract:Orthopaedic materials may improve its capacity to resist bacterial adherence, and subsequent infection. Our aim was to test the bacterial adherence to alpha-tocopherol (frequently named vitamin E, VE) doped or blended UHMWPE with S. aureus and S. epidermidis, compared to virgin material. Collection strains and clinical strains isolated from patients with orthopaedic infections were used, with the biofilm-developing ability as a covariable. While collection strains showed significantly less adherence to VE-UHMWPE, some clinical strains failed to confirm this effect, leading to the conclusion that VE doped or blended UHMWPE affects the adherence of some S. epidermidis and S. aureus strains, independently of the concentration in use, but the results showed important intraspecies differences and cannot be generalized.
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