A highly reliable integrated PDMS interconnector with a long cast flange for microfluidic systems |
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Authors: | Hong-long Chang Feng Zhang Ji-liang Ding Fang-lu Chen Shui-jin Hong Michael Kraft Wei-zheng Yuan |
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Affiliation: | 1. Micro and Nano Electromechanical System Lab, Northwestern Polytechnical University, Xi’an, China 2. Caltech Micromachining Lab, California Institute of Technology, CA, USA 3. School of Electronics and Computer Science, University of Southampton, Southampton, UK
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Abstract: | This paper presents a highly reliable macro to micro domain interconnection technology for microfluidic applications using Polydimethylsiloxane (PDMS) casting techniques. Characteristic to the interconnectors are long flanges fabricated in the PDMS film; therefore the contact area between PDMS and tubes is considerably increased compared to other interconnection technologies. Thus, both glass capillaries and Polytetrafluoroethylene (PTFE) tubes can be held in position very reliably and rigidly. To test the reliability of the interconnectors, PTFE tubes were successfully connected to microfluidic chips without the aid of any liquid adhesives. Both leakage and pull-out tests demonstrated the functionality and reliability of the PDMS interconnectors; no leakage was detected under a working pressure up to 400?kPa. A pull-out test yielded a pull-out force of 22.45?N. Furthermore, once a casting mould is fabricated, it can be re-used as a template repeatedly achieving a low cost technology and making it suitable for batch production. |
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