| 作为基因载体的低分子量壳聚糖的制备及研究进展 |
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| 引用本文： | 罗霄,姚晓. 作为基因载体的低分子量壳聚糖的制备及研究进展[J]. 化学与生物工程, 2009, 26(10): 18-21 |
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| 作者姓名： | 罗霄 姚晓 |
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| 作者单位： | 南京工业大学材料科学与工程学院,江苏,南京,210009;南京工业大学材料科学与工程学院,江苏,南京,210009 |
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| 摘 要： | 低分子量壳聚糖作为非病毒性基因治疗载体有着广阔的前景,已成为研究的热点。综述了低分子量壳聚糖的制备方法以及载基因的研究进展,并讨论了影响转染的因素。
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| 关 键 词： | 低分子量壳聚糖 制备 基因载体 基因转染 |
The Preparation and Research Progress of Low Molecular Weight Chitosan as Gene Vector |
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| LUO Xiao,YAO Xiao. The Preparation and Research Progress of Low Molecular Weight Chitosan as Gene Vector[J]. Chemistry & Bioengineering, 2009, 26(10): 18-21 |
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| Authors: | LUO Xiao YAO Xiao |
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| Affiliation: | LUO Xiao,YAO Xiao(College of Materials Science and Engineering,Nanjing University of Technology,Nanjing 210009,China) |
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| Abstract: | Low molecular weight chitosan,which has a widely prospect as non-viral gene therapy vector,has become a research focus.This paper reviews the preparation method of low molecular weight chitosan and the research progress of carrier gene,and discusses the factors affecting on the transfection. |
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| Keywords: | low molecular weight chitosan preparation gene vector gene transfection |
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