| NaCl添加量对SF/HA复合多孔材料结构和性能的影响 |
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| 引用本文： | 张琴,罗淼良,张强,刘雨,李明忠. NaCl添加量对SF/HA复合多孔材料结构和性能的影响[J]. 苏州大学学报(工科版), 2009, 29(4) |
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| 作者姓名： | 张琴 罗淼良 张强 刘雨 李明忠 |
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| 作者单位： | 1. 苏州大学纺织与服装工程学院,江苏苏州,215021;苏州市生物组织工程与技术重点实验室,江苏苏州,215021
2. 苏州大学纺织与服装工程学院,江苏苏州,215021 |
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| 基金项目： | 国家973计划课题，江苏省高校自然科学重大基础研究项目 |
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| 摘 要： | 采用等静压成型法制备丝素SF/羟基磷灰石HA复合多孔材料,通过对材料形态结构、密度、孔隙率、透气性及抗弯、抗压性能等的测试和分析,研究了致孔剂NaCl添加量对SF/HA复合多孔材料结构和性能的影响.结果表明,以Nacl为致孔剂能够制得SF/HA复合多孔材料,致孔效果明显,孔呈三维空间结构,当NaCl添加量达到400%～550%后,材料内孔与孔之间连通性有较显著的改善.SF/HA复合多孔材料的孔结构有利于养料和代谢物的运输交换,为细胞提供良好的生长环境,便于骨组织的长入,其生物降解性有利于骨组织的改建和塑形,具有良好的临床应用前景.
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| 关 键 词： | 丝素蛋白 羟基磷灰石 复合材料 孔结构 骨修复 |
Effects of Addition Amount of NaCl Porogen on the Structure and Properties of the Porous Silk Fibroin (SF)/Hydroxyapatite (HA) Composites |
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| Zhang Qin,Luo Miao-liang,Zhang Qiang,Liu Yu,Li Ming-zhong. Effects of Addition Amount of NaCl Porogen on the Structure and Properties of the Porous Silk Fibroin (SF)/Hydroxyapatite (HA) Composites[J]. Journal of Suzhou University(Engineering Science Edition), 2009, 29(4) |
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| Authors: | Zhang Qin Luo Miao-liang Zhang Qiang Liu Yu Li Ming-zhong |
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| Affiliation: | 1.School of Textile and Clothing Engineering;Suzhou University;Suzhou 215021;China;2.Suzhou Key Laboratory of Tissue Engineering Material Science and Technology;China |
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| Abstract: | In this paper,we aimed to investigate the effects on the structure and properties of the porous silk fibroin(SF)/hydroxyapatite(HA) composites with the addition amount of NaCl particles as porogen.Here,the SF/HA composites were fabricated by means of isostatic pressing and evaluated for their morphology,average pore size,porosity,MIP,air permeability and mechanical testing.These results showed that NaCl particles porogen used for porous SF/HA composites was available,the pores obtained were obvious and pres... |
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| Keywords: | NaCl |
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