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2-Substituted-4-methoxybenzimidazole-based PDE4 inhibitors |
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| Authors: | J Regan J Bruno D McGarry G Poli B Hanney S Bower J Travis D Sweeney B Miller J Souness S Djuric |
| Affiliation: | Rh?ne-Poulenc Rorer, Collegeville, PA 19426, USA. |
| Abstract: | A new family of PDE4 inhibitors based on a benzimidazole framework is described. Several of these compounds are orally bioavailable and show efficacy in in vivo models of inflammatory disease. |
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