| Preparation and Degradation Characteristics of Poly(d,1-laetide) Composite Films |
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| 引用本文： | 陈蕾,李世普. Preparation and Degradation Characteristics of Poly(d,1-laetide) Composite Films[J]. 武汉理工大学学报(材料科学英文版), 2007, 0(4) |
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| 作者姓名： | 陈蕾 李世普 |
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| 作者单位： | Biomedical Materials and Engineering Research Center Wuhan University of Technology，Biomedical Materials and Engineering Research Center，Wuhan University of Technology，Wuhan 430070，China，Wuhan 430070，China |
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| 基金项目： | Funded by“973”Project(No.2005CB623905) |
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| 摘 要： | PDLLA/CHI/β-TCP/NGF composite films were prepared by a solvent evaporation method. The degradation characteristics of the poly(d,1-lactide)composite films were studied in vitro and in vivo. The acidity produced by poly(d,1-lactide)materials was not obvious.Adding chitosan andβ-TCP can relieve the acidity problem and improve strength performance of films.The NGF has influences on the degradation characteristics of films.It is verified that PDLLA/CHI/β-TCP/NGF composite films prepared by solvent evaporation method have excellent degradation characteristics.It can be used as a perfect biomaterial for repairing nerve injuries.
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| 关 键 词： | poly(d 1-lactic acid)(PDLLA) chitosan(CHI) β-TCP nerve growth factor(NGF) degradation characteristics |
Preparation and Degradation Characteristics of Poly(d,1-laetide) Composite Films |
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| CHEN Lei YAN Yuhua LI Jianhua LI Shipu. Preparation and Degradation Characteristics of Poly(d,1-laetide) Composite Films[J]. Journal of Wuhan University of Technology. Materials Science Edition, 2007, 0(4) |
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| Authors: | CHEN Lei YAN Yuhua LI Jianhua LI Shipu |
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| Affiliation: | CHEN Lei YAN Yuhua LI Jianhua LI Shipu* |
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