<i>Coxiella burnetii:</i> living inside the host cell |
| |
Authors: | Jesus Sebastian DISTEL Walter BERON Rodolfo Matias ORTIZ FLORES |
| |
Affiliation: | 1
Instituto de Histología y Embriología de Mendoza (IHEM), CONICET, Universidad Nacional de Cuyo, Mendoza, Argentina
2
Facultad de Odontología, Universidad Nacional de Cuyo, Mendoza, Argentina |
| |
Abstract: | Coxiella burnetii is an obligate intracellular pathogen and the causative agent of Q fever. In this brief review, we describe how recently described mechanisms help our understanding of C. burnetii invasion and its survival in the host cell by the formation of a replicative niche: the Coxiella-containing vacuole. We describe the actin-associated proteins involved in the internalization of C. burnetii, and we discuss the contribution of diverse degradation pathways of the cell during the formation and stabilization of the Coxiella-containing vacuole. |
| |
Keywords: | Actin Coxiellosis Phagocytic pathway Q fever |
|
| 点击此处可从《Biocell》浏览原始摘要信息 |
|
点击此处可从《Biocell》下载全文 |
|