| 转铁蛋白的研究进展 |
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| 引用本文： | 赵建辉,韩柱,侯小康.转铁蛋白的研究进展[J].河北化工,2010,33(9):34-36. |
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| 作者姓名： | 赵建辉 韩柱 侯小康 |
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| 作者单位： | 1. 华北制药新药研究开发有限公司,河北,石家庄,050015
2. 河北中润制药有限公司,河北,石家庄,050046 |
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| 摘 要： | 转铁蛋白（Transferrin,TRF,TF,又称为铁传递蛋白、血清运铁蛋白、运铁蛋白、嗜铁蛋白、铁糖蛋白）是一种重要的β-球蛋白,是脊椎动物体内铁的运输者。1945年,Holmberg和Laurell首次在人血清中发现了这种非血红素结合铁的转铁蛋白,此后人们又在哺乳动物以及鱼类、两栖类及爬行类的血清中分别发现了转铁蛋白的存在。由于在抗菌、杀菌以及在肿瘤和癌症防治等方面的突出作用,转铁蛋白在医药界已越来越受到人们的重视并开展了转铁蛋白作为药物载体的大量研究。
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| 关 键 词： | 转铁蛋白 TRF TF 药物载体 |
Study Progress of Transferrin |
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| ZHAO Jian-Hui,HAN Zhu,HOU Xiao-kang.Study Progress of Transferrin[J].Hebei Chemical Engineering and Industry,2010,33(9):34-36. |
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| Authors: | ZHAO Jian-Hui HAN Zhu HOU Xiao-kang |
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| Affiliation: | 1.NCPC New Drug Research and Development Co.,Ltd,Shijiazhuang 050015,China;2.Hebei Zhongrun Pharmaceutical Co.,Ltd,Shijiazhuang 050046,China) |
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| Abstract: | Transferrin（TRF,TF） is a kind of important beta globulin,vertebrates iron shippers.In 1945,Holmberg and Laurell first in serum found this combination nonheme iron transferrin,then people in mammals and fish,amphibians and reptiles were found in serum transferrin existence.Due to the antibacterial,sterilization and tumor and cancer preven-tion,etc,transferrin in pharmaceutical industry has become more and more attention,people developed transferrin as drug carrier of research. |
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| Keywords: | TRF TF |
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