Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices |
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| Authors: | Giuntini F Dumoulin F Daly R Ahsen V Scanlan E M Lavado A S P Aylott J W Rosser G A Beeby A Boyle R W |
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| Affiliation: | Department of Chemistry, University of Hull, Kingston-upon-Hull, East Yorkshire, HU6 7RX, UK. |
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| Abstract: | Polyacrylamide nanoparticles bearing two orthogonal reactive functionalities were prepared by reverse microemulsion polymerisation. Water-soluble photosensitisers and peptide or carbohydrate moieties were sequentially attached to the new nanospecies by orthogonal conjugations based on copper-catalysed azide-alkyne cycloaddition and isothiocyanate chemistry. |
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