| 提高甲氨基阿维菌素苯甲酸盐胺化还原反应转化率的工艺技术研究 |
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| 引用本文： | 杨永军. 提高甲氨基阿维菌素苯甲酸盐胺化还原反应转化率的工艺技术研究[J]. 云南化工, 2019, 0(3) |
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| 作者姓名： | 杨永军 |
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| 作者单位： | 华北制药集团爱诺有限公司 |
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| 摘 要： | 甲氨基阿维菌素苯甲酸盐是从发酵产品阿维菌素B1开始合成的一种新型高效半合成抗生素杀虫剂,它具有超高效,低毒(制剂近无毒),无残留,无公害等生物农药的特点。通过工艺技术优化,进一步提高提高甲氨基阿维菌素苯甲酸盐胺化还原反应转化率水平(5.7%),更加利于降低生产成本,扩大市场应用。
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| 关 键 词： | 甲氨基阿维菌素 胺化还原反应 转化率 |
Studies on the Improving of the Conversion Rate of Reductive Amination for Emamectin Benzoate |
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| Affiliation: | ,North China Pharmaceutical Group Aino Co., Ltd. |
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| Abstract: | As a novel semi-synthetic antibiotics synthesized from the fermentation product of compound avermectin B1, Emamectin Benzoate is characterized with ultra-high efficacy and low toxicity(nearly non-toxic for the drug product made using it). It has almost no residue to be found and thus is safe to the environment. Through the technical optimization and/or innovation, the conversion rate of the reductive amination for Emamectin Benzoate was improved by 5.7%, which is anticipated to be greatly reducing the production costs and promoting its market expansion. |
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| Keywords: | Emamectin Benzoate reductive amination conversion rate |
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