Low energy helium ion texturization of titanium and relevance to biomedical applications |
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Authors: | Nicholas A. Riedel Tyler B. Cote Samuel L. Bechara Ketul C. Popat John D. Williams |
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Affiliation: | 1. Department of Mechanical Engineering, Colorado State University, Fort Collins, CO 80523, United States;2. Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, CO 80523, United States;3. School of Biomedical Engineering, Colorado State University, Fort Collins, CO 80523, United States |
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Abstract: | Helium irradiation of metals has long been studied in efforts to understand the damaging aspects associated with applications in fusion reactors and tritium storage. This work examines the possibility of using low energy helium ion bombardment as a method of producing a beneficial surface texturization to promote bone growth on orthopedic implants. Using 300 eV helium ions, two unique porous titanium surfaces were created when substrates were held at temperatures of roughly 450 °C and 600 °C. The surfaces were physically characterized by scanning electron microscopy (SEM) and scanning white light interferometry. A week long hFOB 1.19 cell culture was performed using an untreated titanium control to evaluate the suitability of these surfaces for orthopedic implants. Cell health and viability were evaluated by calcein AM live cell staining, MTT assay, and SEM. The results show that helium texturizations promote cellular activity and have no detrimental effect on cell health. |
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Keywords: | Titanium Helium Ion bombardment Implant hFOB 1.19 Porous |
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