Electrospun composite fibers of polyvinylpyrrolidone with embedded poly(methyl methacrylate)–polyethyleneimine core–shell particles |
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Authors: | Thammasit Vongsetskul Phornpimon Kongjumnean Panya Sunintaboon Ratthapol Rangkupan Pramuan Tangboriboonrat |
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Affiliation: | 1. Department of Chemistry, Faculty of Science, Mahidol University, Rama VI Road, Phyathai, Bangkok, 10400, Thailand 2. Metallurgy and Materials Science Research Institute, Chulalongkorn University, Phyathai Road, Pathumwan, Bangkok, 10330, Thailand 3. Center of Innovative Nanotechnology, Chulalongkorn University, Phyathai Road, Pathumwan, Bangkok, 10330, Thailand
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Abstract: | Composite fibers consisting of poly(methyl methacrylate)–polyethyleneimine (PMMA–PEI) core–shell particles embedded in polyvinylpyrrolidone (PVP) were successfully fabricated by the electrospinning method. The electrospun fibers were produced using 18?% w/v aqueous PVP solution blended with 2?% w/v PMMA–PEI particles at various pH (1, 2, 3, and 4) with a fiber collection distance set at 10?cm. The applied electrical voltages (10, 12, 14, and 16?kV) significantly affected the morphology and diameter of the prepared composite fibers (141–353?nm). The smallest composite fibers were obtained from the spinning mixture at pH 2 and a voltage of 14?kV. The composite fibers would potentially be applied as drug and bioactive compound carriers. |
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