| 蜂王浆产品中10-羟基-2-癸烯酸的含量稳定性研究 |
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| 引用本文： | 党亚丽,张中健,闫小伟. 蜂王浆产品中10-羟基-2-癸烯酸的含量稳定性研究[J]. 办公自动化, 2011, 0(16): 44-45,26 |
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| 作者姓名： | 党亚丽 张中健 闫小伟 |
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| 作者单位： | 浙江省医学科学院药物研究所 |
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| 基金项目： | 浙江省医科院药物所资助项目A11005S |
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| 摘 要： | 10-羧基-2-癸烯酸(10-HDA)是蜂王浆特有的不饱和脂肪酸,在其质量标准中特别规定了其含量要求。采用纳米技术制备纳米脂质体可提高其稳定性,本文以包封率为评定指标,采用乙醇注入-超声法制备了10-HDA纳米脂质体,并用液相色谱测定其中的10-HDA含量,比较了五种蜂王浆产品中10-HDA的含量稳定性。结果发现,10-HDA纳米脂质体包封率可达98.3%,同时其含量最为稳定,而其它四种蜂王浆产品中10-HDA含量不稳定,随着时间的延长呈下降趋势。
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| 关 键 词： | 10-HDA含量 蜂王浆产品 稳定性 脂质体 |
Study on the Stability of 10-Hydroxy-2-Decenoic Acid Content in Royal Jelly Product |
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| Dang Yali Zhang Zhongjian Yan Xiaowei. Study on the Stability of 10-Hydroxy-2-Decenoic Acid Content in Royal Jelly Product[J]. Office Automation, 2011, 0(16): 44-45,26 |
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| Authors: | Dang Yali Zhang Zhongjian Yan Xiaowei |
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| Affiliation: | (Institute of Materia Medica,Zhejiang Academy of Medical Sciences Hangzhou 310013) |
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| Abstract: | 10-hydroxy-2-decenoic acid(10-HDA) is the special unstaturated fatty acid in royal jelly,which content is ruled in its quality.the lecithin as the main wall material,the 10-HDA nanoliposome was prepared by the ethanol injection-sonication method.Furthermore,five kinds of royal jelly product as the material,the content of 10-HDA was measured by HPLC,and then the 3 month-long stability experiment was carried out.Results showed that the envelope rate of 10-HDA may reach 90.3% using nanocapsule technology to prepare 10-HDA nanoliposome;simultaneously its content stability could be improved.While the 10-HAD content of other four kind of royal jelly production was unstable,the content became lower along with the time. |
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| Keywords: | 10-HDA content Royal jelly product Stability Nanoliposome |
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