Preparation and Application of Iron‐substituted (Z)‐Enals: Synthesis of 5‐Substituted α,β‐Butenolides |
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Authors: | Mark Mikulá s,Christian Mö ller,Sybille Rust,Frank Wierschem,Patrick Amrhein,Karola Rü ck‐Braun |
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Abstract: | A reaction sequence furnishing cyclic β‐[η5‐C5H5(CO)2Fe]‐substituted enals 5 starting from β‐keto esters 1 is described. Organolithiums were found to react smoothly with the iron‐substituted enals yielding α,β‐butenolides 6 by an intramolecular cyclocarbonylation of the lithiumalkoxide initially formed. The influence of e.g. the reaction temperature and the solvent on the reaction cascade is discussed. A reaction mechanism is proposed. |
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Keywords: | Carbonylations Iron Lactams Lactones Lithium |
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