In unison: regularization of protein secondary structure predictions that makes use of multiple sequence alignments |
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Authors: | K Zimmermann JF Gibrat |
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Affiliation: | Unité de Bio-Informatique, INRA, Jouy-en-Josas, France. |
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Abstract: | We present a method whose purpose is to post-process the fuzzy results of secondary structure prediction methods that use multiple sequence alignments, in order to obtain 'realistic' secondary structures, i.e., secondary structure elements whose length is greater than or equal to some predefined minimum length. This regularization helps with interpretation of the secondary structure prediction. |
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