| 壳聚糖及壳聚糖-羧甲基纤维素钠复合囊材的体外降解性能研究 |
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| 引用本文： | 莫名月,李国明. 壳聚糖及壳聚糖-羧甲基纤维素钠复合囊材的体外降解性能研究[J]. 广东化工, 2009, 36(6): 50-51,254 |
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| 作者姓名： | 莫名月 李国明 |
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| 作者单位： | 华南师范大学,化学与环境学院,广东,广州,510631;华南师范大学,化学与环境学院,广东,广州,510631 |
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| 摘 要： | 制备了CS膜、交联CS膜、交联CS／CMCNa双层、多层复合膜以及ECH交联多层复合膜，考察了交联cs膜在不同介质中的降解，比较了上述几种膜材料在溶菌酶PBS溶液中的降解情况，对不同囊材载药微囊进行了体外降解实验。结果表明，交联cs膜在溶菌酶PBS溶液中降解速率最大。膜材料在溶菌酶PBS溶液中的降解速率与交联程度有关，载药微囊可以被溶菌酶降解。
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| 关 键 词： | 壳聚糖 羧甲基纤维素钠 复合囊材 降解 |
In-vitro Degradation Properties of Chitosan and Chitosan/Sodium Carbonxymethyl Cellulose Composite Materials |
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| Mo Mingyue,Li Guoming. In-vitro Degradation Properties of Chitosan and Chitosan/Sodium Carbonxymethyl Cellulose Composite Materials[J]. Guangdong Chemical Industry, 2009, 36(6): 50-51,254 |
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| Authors: | Mo Mingyue Li Guoming |
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| Affiliation: | Mo Mingyue,Li Guoming (School of Chemistry and Environment,South China Normal University,Guangzhou 510631,China) |
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| Abstract: | CS film, crosslinking CS film, crosslinking CS/CMCNa double-layer composite film, crosslinking CS/CMCNa multilayer composite film and CS/CMCNa multilayer film crosslinked with ECH were prepared. Degradation of crosslinking CS film in different medium was investigated. In-vitro degradation of films above was compared in lysozyme PBS buffer solution. In-vitro degradation experiments of microcapsule with these film materials were carried. The results indicated that degradation speed of crosslinking CS film in ... |
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| Keywords: | chitosan sodium carbonxymethyl cellulose composite material degradation |
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