| 食品中环己基氨基磺酸钠的液相色谱串联质谱测定方法的改进 |
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| 引用本文： | 马雪丰. 食品中环己基氨基磺酸钠的液相色谱串联质谱测定方法的改进[J]. 包装与食品机械, 2017, 35(2). DOI: 10.3969/j.issn.1005-1295.2017.02.016 |
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| 作者姓名： | 马雪丰 |
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| 作者单位： | 重庆市食品药品检验检测研究院,重庆,401121 |
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| 摘 要： | 对目前采用的测定食品中环己基氨基磺酸钠的液相色谱串联质谱法SN/T 1948-2007进行了改进。通过优化质谱条件,在ESI负离子模式下,根据选择的特征离子,结合保留时间,发现另一个裂解离子对(178.0/96.0)可作为定性分析,实现负离子模式下同时定性定量分析。采用改进的方法,环己基氨基磺酸钠在1~400 ng/m L范围内具有良好的线性相关性,相关系数0.9999;加标回收率在84.6%~101.2%之间,检出限为0.01mg/kg。本方法操作简便、快捷、准确可靠,适用于食品中环己基氨基磺酸钠的测定。
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| 关 键 词： | 环己基氨基磺酸钠 食品 方法改进 液相色谱串联质谱法 |
Improvement for Determination of Sodium Cyclamate in Foods by Liquid ChromatographyTandem Mass Spectrometry |
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| MA Xue-feng. Improvement for Determination of Sodium Cyclamate in Foods by Liquid ChromatographyTandem Mass Spectrometry[J]. Packaging and Food Machinery, 2017, 35(2). DOI: 10.3969/j.issn.1005-1295.2017.02.016 |
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| Authors: | MA Xue-feng |
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| Abstract: | The method of SN/T 1948-2007 which used to determinate of sodium cyclamate in foods by liquid chromatography tandem mass spectrometry was improved.By optimizing MS conditions in ESI negative mode,depending on the selected characteristic ions and the retention time which found another cracking ion pair(178.0 / 96.0) can be used as qualitative analysis,while the negative ion mode to achieve qualitative and quantitative analysis.The results showed that the improved method displayed good linearity over the range 1 to 400ng/mL with a correlation coefficient of 0.9999.The average recovery of spiked sample ranged from 84.6% to 101.2% and the minimum detection limit was 0.01mg/kg.This improved method is simple,rapid,accurate and reliable and can be used for determination of sodium cyclamate in foods. |
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| Keywords: | sodium cyclamate food method improvement HPLC-MS/MS |
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