| 氯乙酸异丙酯的催化合成 |
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| 引用本文： | 毛建新 吴为强. 氯乙酸异丙酯的催化合成[J]. 精细石油化工, 1999, 0(4): 28-30 |
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| 作者姓名： | 毛建新 吴为强 |
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| 作者单位： | 浙江大学催化研究所!杭州，310028，浙江大学催化研究所!杭州，310028，浙江大学催化研究所!杭州，310028，浙江大学催化研究所!杭州，310028 |
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| 摘 要： | 氯乙酸异丙酯是合成消炎镇痛药萘普生的重要原料。研究了几种固体路易斯酸对其合成的催化效果 ,发现六水合氯化铁最好。讨论了合成的影响因素以及找出了最佳工艺条件。
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| 关 键 词： | 氯乙酸异丙酯 六水合氯化铁 催化合成 |
CATALYTIC SYNTHESIS OF ISOPROPYL CHLOROACETATE |
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| Mao Jianxin,Wu Weiqiang,Jiang Xiaoyuan and Gu Miaolan. CATALYTIC SYNTHESIS OF ISOPROPYL CHLOROACETATE[J]. Speciality Petrochemicals, 1999, 0(4): 28-30 |
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| Authors: | Mao Jianxin Wu Weiqiang Jiang Xiaoyuan Gu Miaolan |
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| Abstract: | Isopropyl chloroacetate was an important synthesis raw material of naproxen, which was a medicine used in diminishing inflammation and analgesia. The catalytic effects of several solid Lewis acids were studied in isopropyl chloroacetate synthesis. It was found that FeCl 3·6H 2O was the best catalyst. The factors influenced the synthesis were discussed and the best condition was found out. |
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| Keywords: | isopropyl chloroacetate FeCl_3·6H_2O catalytic synthesis |
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