1. Department of Applied Chemistry, Faculty of Science, University of Mohaghegh Ardabili, P.O. Box 56199–11367, Ardabil, Iran;2. Department of Chemistry, Faculty of Science, University of Kurdistan, Sanandaj, Iran
Abstract:
A highly efficient solvent-free and simple one-pot approach for the synthesis of 4-hydroxythiazolidine-2-thione is described. The reaction of primary amines and carbon disulfide in the presence of 2-chloroacetaldehyde afforded the title compounds in high yields.