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A convenient solvent-free and one-pot synthesis of 4-hydroxythiazolidine-2-thiones |
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| Authors: | Farough Nasiri Amin Zolali Mohammad Ahmadiazar |
| Affiliation: | 1. Department of Applied Chemistry, Faculty of Science, University of Mohaghegh Ardabili, P.O. Box 56199–11367, Ardabil, Iran;2. Department of Chemistry, Faculty of Science, University of Kurdistan, Sanandaj, Iran |
| Abstract: | A highly efficient solvent-free and simple one-pot approach for the synthesis of 4-hydroxythiazolidine-2-thione is described. The reaction of primary amines and carbon disulfide in the presence of 2-chloroacetaldehyde afforded the title compounds in high yields. |
| Keywords: | 2-chloroacetaldehyde primary amines dithiocarbamate carbon disulfide |