自身免疫性溶血性贫血患者成分输血的疗效观察

目的探讨自身免疫性溶血性贫血(AHIA)患者成分输血的临床疗效。方法对15例输注洗涤红细胞的AHIA患者(A组)和15例输注红细胞悬液的AHIA患者(B组)的临床资料进行回顾性对比分析。结果 A、B两组患者输血24h后,血红蛋白(Hb)、红细胞(RBC)数量和血细胞比容(Hct)均升高;同组内输血前后比较,差异均有统计学意义;两组间输血前后差异均无统计学意义。A组中5例患者输注洗涤红细胞联合血浆置换治疗AHIA,临床症状明显改善。结论输注洗涤红细胞与红细胞悬液治疗AHIA,其临床效果差异无统计学意义;输注洗涤红细胞联合血浆置换治疗AHIA效果显著。

Curative Effect of Component Blood Transfusion on Autoimmune Hemolytic Anemia

Objective To investigate the curative effect of component blood transfusion on autoimmune hemolytic anemia(AHIA)in clinic.Methods The clinical data on 15 patients with AHIA transfused with washed red cells(group A)and 15 patients transfused with suspended red cells(group B)were reviewed and compared.Results The Hb,RBC and Hct of patients in both groups A and B increased 24 h after transfusion.All the indexes showed significant difference in the same group before and after transfusion,while showed no significant difference between the two groups.The clinical symptoms of 5 patients in group A improved significantly after treatment by transfusion of washed red cells combined with plasma exchange.Conclusion Transfusion with washed red cells and with suspended red cells showed no significant difference in clinical curative effect.However,the transfusion with washed red cells combined with plasma exchange showed significantly curative effect on AHIA.