单次注入氚水后氚在孕鼠体内的代谢和转移

METABOLISM DISTRIBUTION AND TRANSFER OF TRITIUM IN PREGNANT MICE AFTER EXPOSURE TO TRITWM WATER

Tritium water with three kind of different dose was singleinjected intraperitoneally to pregnant mice in tbe various time. The tritiumconcentration in the tissues from mother mice were measured on the 3.5 days aftermother mice parturition. Dose rates in baby mice were estimated, as well as thetransfer coefficient of tritium from mother mice to baby mice calculated based on thetritium concentrations. The results of the experiment showed that tritium was almostuniformly distributed among the tissues after exposure to tritiated water at threeexperimental groups. However, it was found that relative concentrations of tritiumin the baby mice tissues were consistently higher than that in mother mice tissues forthree experimental groups. The relative concentration of tritium in the tissues wasnot affected by the different dose but developing on the exposure time. The resultsof radiation dose rates from baby mice estimation at the end of exposure showedthat the higher radiation dose rates was found in the md to tritiated waterduring 7.5 days. The transfer coefficient of tritium from mother mice into baby mice was almostno different among the three radiation dose groups. The highest transfer coefficientwas observed in mother mice exposed to tritiated water during 16.5 days, howeverit was not found that transfer coefficient were higher in the mother mice exposedto tritiated water during 11.5 days than that of 7.5 days.