| Surface Modification of Polyethylene by Heparin for Improvement of Antithrombogenicity |
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| 作者姓名： | 赵国巍 陈亚芍 董涛 王晓丽 |
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| 作者单位： | Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Materials Science, Shanxi Normal University, Xi＇an 710062, China |
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| 基金项目： | support by National Natural Science Foundation of China （No. 10675078） |
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| 摘 要： | The purpose of this paper was to enhance blood compatibility of polyethylene （PE） film. PE film pretreated by argon plasma was subjected to ultraviolet （UV） -induced graft polymerization with Acrylic acid（AAc） （AAc-grafted PE films, PE-g-PAAc） without photo-initiator, then heparin was covalently immobilized on the PE surface （PE-g-HPAAc）. The surface properties and microstructure of PE-g-PAAc and PE-g-HPAAc were studied by static contact angle measurement, atomic force microscope （AFM）, X-ray photoelectron spectroscopy （XPS） and Attenuated total reflectance Fourier transfer infrared spectroscopy （ATR-FTIR）. It was confirmed that AAc and heparin were successfully immobilized onto the surface of PE film. Results of platelet adhesion experiments indicated that the antithrombogenicity of the modified PE film was remarkably improved.
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| 关 键 词： | 聚乙烯 血液兼容性 表面改性 肝素 抗血栓发生作用 |
| 修稿时间： | 2006-03-21 |
Surface Modification of Polyethylene by Heparin for Improvement of Antithrombogenicity |
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| ZHAO Guowei , CHEN Yashao, DONG Tao, WANG Xiaoli.Surface Modification of Polyethylene by Heparin for Improvement of Antithrombogenicity[J].Plasma Science & Technology,2007,9(2):202-205. |
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| Authors: | ZHAO Guowei CHEN Yashao DONG Tao WANG Xiaoli |
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| Affiliation: | [1]Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Materials Science, Shanxi Normal University, Xi'an 710062, China |
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| Abstract: | plasma, UV-induced graft, PE film, antithrombogenicity |
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| Keywords: | plasma UV-induced graft PE film antithrombogenicity |
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