| A Preliminary Study of the Application of a Model Animal-Caenorhabidity elegans＇ Exposure to a Low-Energy Ion Irradiation System |
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| 引用本文： | 刘雪兰 蔡克周 冯慧云 许安 袁航 余增亮. A Preliminary Study of the Application of a Model Animal-Caenorhabidity elegans＇ Exposure to a Low-Energy Ion Irradiation System[J]. 等离子体科学和技术, 2007, 9(5): 634-637 |
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| 作者姓名： | 刘雪兰 蔡克周 冯慧云 许安 袁航 余增亮 |
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| 作者单位： | Key Laboratory of Ion Beam Bioengineering, Institute of Plasma Physics,Chinese Academy of Science, Hefei 230031, China |
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| 摘 要： | Because of the lack of suitable animal models adapted to high vacuum stress in the low-energy ion implantation system, the bio-effects ion irradiation with an energy less than 50 keV on multi-cellular animal individuals have never been investigated so far. The nematode Caenorhabditis elegans has proved to be an excellent animal model used for the study of a broad spectrum of biological issues. The purpose of this work was to investigate the viability of this animal under ion irradiation. We studied the protection effects of glycerol and trehalose on the enhancement of nematodes＇ ability to bear the vacuum stress. The results showed that the survival of the nematodes was enhanced remarkably under long and slow desiccation, even without glycerol and trehalose. 159 glycerol showed a better anti-vacuum stress effect on the nematodes than trehalose did under short-time desiccation. Low-temperature pre-treatment or post-treatment of the samples had no obvious effect on the survival scored after argon ion irradiation. Moreover, little effect was induced by 15% glycerol- and vacuum-exposure on germ cell apoptosis, compared to the untreated control sample. It issuggested that such treatment would provide relatively low background for genotoxic evaluations with ion irradiation.
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| 关 键 词： | 低能氩离子辐射系统 多细胞动物 基因突变 等离子体 |
| 修稿时间： | 2006-11-10 |
A Preliminary Study of the Application of a Model Animal-Caenorhabidity elegans＇ Exposure to a Low-Energy Ion Irradiation System |
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| LIU Xuelan , CAI Kezhou , FENG Huiyun ,XU An, YUAN Hang , YU Zengliang. A Preliminary Study of the Application of a Model Animal-Caenorhabidity elegans＇ Exposure to a Low-Energy Ion Irradiation System[J]. Plasma Science & Technology, 2007, 9(5): 634-637 |
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| Authors: | LIU Xuelan CAI Kezhou FENG Huiyun XU An YUAN Hang YU Zengliang |
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| Affiliation: | Key Laboratory of Ion Beam Bioengineering, Institute of Plasma Physics Chinese Academy of Science, Hefei 230031, China |
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| Abstract: | low-energy argon ions, Caenorhabditis elegans, multi-cellular animal individual |
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| Keywords: | low-energy argon ions Caenorhabditis elegans multi-cellular animal individual |
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