|
|||||
|
|
Biomimetic Tendrils by Four Dimensional Printing Bimorph Springs with Torsion and Contraction Properties Based on Bio-Compatible Graphene/Silk Fibroin and Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) |
|
| Authors: | Carmelo De Maria Irene Chiesa Davide Morselli Maria Rachele Ceccarini Silvia Bittolo Bon Micaela Degli Esposti Paola Fabbri Antonino Morabito Tommaso Beccari Luca Valentini |
| Affiliation: | 1. Department of Information Engineering and Research Center E. Piaggio, University of Pisa, Largo Lucio Lazzarino 1, Pisa, 56122 Italy;2. Department of Civil, Chemical, Environmental and Materials Engineering (DICAM), Università di Bologna, Via Terracini 28, Bologna, 40131 Italy National Interuniversity Consortium of Materials Science and Technology (INSTM), Via Giusti 9, Firenze, 50121 Italy;3. Department of Pharmaceutical Sciences, University of Perugia, Perugia, 06123 Italy;4. National Interuniversity Consortium of Materials Science and Technology (INSTM), Via Giusti 9, Firenze, 50121 Italy Dipartimento di Ingegneria Civile e Ambientale, Università degli Studi di Perugia, Strada di Pentima 4, Terni, 05100 Italy;5. Department of Pediatric Surgery, Meyer Children's Hospital, Viale Pieraccini 24, Firenze, 50139 Italy Dipartimento Neuroscienze, Psicologia, Area del Farmaco e della Salute del Bambino NEUROFARBA, Università degli Studi di Firenze, Viale Pieraccini 6, Firenze, 50121 Italy;6. National Interuniversity Consortium of Materials Science and Technology (INSTM), Via Giusti 9, Firenze, 50121 Italy |
| Abstract: | Taking inspiration from plant tendril geometry, in this study, 4D bimorph coiled structures with an internal core of graphene nanoplatelets-modified regenerated silk and an external shell of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) are fabricated by 4D printing. Finite element simulations and experimental tests demonstrate that integrating these biomaterials with different coefficients of thermal expansion results in the temperature induced self-compression and torsion of the structure. The bimorph spring also exhibits reversible contractive actuation after exposure to water environment that paves its exploitation in regenerative medicine, since core materials also have been proven to be biocompatible. Finally, the authors validate their findings with experimental measurements using such springs for temperature-mediated lengthening of an artificial intestine. |
| Keywords: | finite element modeling four-dimensional printing graphene mechanical properties poly(3-hydroxybutyrate-co-3-hydroxyvalerate) regenerated silk self-contracting properties twisting |