| 三光气合成N-硝基-N,N'-二苯基脲的“一锅法”工艺 |
| |
| 引用本文： | 许洪涛,申晓霞,曹丹,李雪刚,陈长水.三光气合成N-硝基-N,N'-二苯基脲的“一锅法”工艺[J].精细化工中间体,2008,38(2):27-29. |
| |
| 作者姓名： | 许洪涛 申晓霞 曹丹 李雪刚 陈长水 |
| |
| 作者单位： | 华中农业大学,理学院,湖北,武汉,430070 |
| |
| 摘 要： | 以N-硝基-2,4,6-三氯苯胺为原料,三光气为酰化剂,一锅法合成N-硝基-N-(2,4,6-三氯苯基)-N′-3,5-二甲基苯基脲。并确定酰化反应的优惠条件为:甲苯作溶剂、三乙胺为催化剂、n(三光气)∶n(N-硝基-2,4,6-三氯苯胺,5)=0.36∶1,反相滴加,反应温度为20℃,反应时间2h,此条件下收率为80%左右。通过元素分析、红外光谱分析、核磁氢谱对产品进行了结构鉴定。
|
| 关 键 词： | “一锅法” 三光气 N-硝基-N N′-二苯基脲 |
| 文章编号： | 1009-9212(2008)02-0027-03 |
| 修稿时间： | 2008年3月9日 |
The Synthesis of N-Nitro-N,N'-diphenyl Urea by One Pot Way Used Triphosgene as Acylating Agent |
| |
| XU Hong-tao,SHEN Xiao-xia,CAO Dan,LI Xue-gang,CHEN Chang-shui.The Synthesis of N-Nitro-N,N'-diphenyl Urea by One Pot Way Used Triphosgene as Acylating Agent[J].Fine Chemical Intermediates,2008,38(2):27-29. |
| |
| Authors: | XU Hong-tao SHEN Xiao-xia CAO Dan LI Xue-gang CHEN Chang-shui |
| |
| Abstract: | The N'-(3,5-dimethylphenyl)-N-nitro-N-(2,4,6-trichlorophenyl)urea were obtained by one pot way based on N-nitro-2,4,6-trichloroaniline used triphosgene as acylating agent.The synthesis technological conditions were discussed. The optimum reaction conditions were obtained as follows:touluene as solvent,triethylamine as catalyst,n(triphosgene)∶n(5)= 0.36 ∶ 1,RP-dropping,temperature was 20℃,reaction time was 2 h,the yield was 80%. And the structures of the products were identified by elementary analysis,infra-red spectrum and nuclear magnetic resonance. |
| |
| Keywords: | one pot way triphosgene N-nitro-N N'-diphenyl urea |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
